Frederick Westhorpe, Ph.D.
Pharmacology
I offer deep expertise in pharmacology and cellular science as they pertain to drug discovery. I specialise in designing robust pharmacological assays, interpreting complex pharmacological data, defining project requirements to meet timelines and budgets, and communicating findings to stakeholders across an organisation.
Example Consulting Topics:
Design and optimisation of pharmacology assays and data evaluation, with emphases on:
> Small molecules
> Understanding polypharmacology
> GPCRs
> Target activation (agonism)
> CNS indications
Building a small molecule portfolio data structures that are future-proof, minable, and AI/ML-ready.
Drug Discovery
I bring extensive experience in leading preclinical drug discovery programs, with a focus on efficiently advancing assets from hit identification to clinical readiness.
Example Consulting Topics:
Strategic planning for hit-to-lead and lead optimisation phases.
Establishing efficient workflows for design-make-test-analyse cycles.
Portfolio prioritisation and resource allocation for early-stage programs.
Gap analysis of preclinical data packages to ensure correct candidate selection and clinical readiness.
Biotech R&D Strategy
Successful biotech companies align scientific goals with corporate objectives, navigate growth challenges, and build effective R&D portfolios. I leverage experience across start-ups, mid-size biotechs, and large pharma to provide tailored advice for sustainable success.
Example Consulting Topics:
R&D portfolio strategy and alignment with corporate vision.
Building scalable preclinical infrastructure for start-ups.
Strategic risk assessments of pipeline projects.
Vendor and CRO management for preclinical programs.
Effective communication of scientific strategy to executive teams and investors.